First discovered α2 Agonists
Least safe
Often used in combination with Ketamine
Ruminants are the most sensitive
Swine are the least sensitive: need for another drug in combination to have an effect
Reliable for Cats
Dose:
SedatoHypnotics: 1-4 mg/kg
Emetics: 0.4-0.5 mg/kg IV, IM
Indication:
SedatoHypnotics
Multimodal Analgesia
Emetics
Adverse effects:
Sedation
Hypotension
Bradycardia