Bacteriostatic Agents

Antibiotics (Etiotropic Agents)

Bacteriostatic Agents: Active ingredient inhibits the growth of bacteria

• After stopping the Antibiotics, the bacteria may grow back
  • Generally the Immune system eliminates the inhibited bacteria so they can’t grow back. It is preferable to use Bactericidal agents for Immunocompromised patients as the bacteria can grow back
• Bacteriostatic Agents have a Bactericidal Agents effect in some cases

Drugs:

• Protein Synthesis Inhibitors:
  • On 30S:
    • Tetracyclines
    • (Spectinomycin)
  • On 50S: Cross resistance
    • Amphenicols
    • Macrolides
    • Lincosamides
    • Pleuromutilins
  • Others:
    • Fusidic Acid
    • Mupirocin
• Folic Acid Pathway Inhibitors:
  • Sulfonamides
  • Diaminopyrimidines